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Am I allowed to test and research with Graphene

I am a student and wanted to do some research on graphene on how to mass produce it and I was wondering before starting my project on the wondrous material. So my question is, Is this a free patent? ...
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Should I do a freedom to operate search if I suspect parts of my product infringe [US]?

Let's say I am building on a high-tech, novel product but that combines several techniques, components and/or innovations that I suspect may be patented (though those may have expired). I would like ...