Consider a patent with broad specification and claims. Would it be considered infringement if one then practices the invention in a way that was not PHOSITA-enabled by the spec/claims at the effective filing date?
As an example, consider an issued patent that claims a method for cutting down trees with a wooden-handled instrument, and describes an example using an ax. If a rogue wizard escaped from Hogwarts to become a lumberjack (bear with me), would using his (wooden) wand with an incantation to cut down trees constitute infringement? Presumably, the original patentee would not have considered this future improvement, but it technically is a subset of the claims.