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My PCT application has more than 100 claims.

I wanna have the strongest protection possible in some countries whereas in others I need some limited protection. [I don't want to waste too much money in claims]

For example, Can I able to remove some claims while applying to USPTO using a PCT application? Or it has to be amended later, after filing the USPTO application?

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Yes, the claims can be amended anytime before first office action. Also, One can reduce number of claims to reduce cost while demand for excess fee payment is pending.

Ref 1 1893.01 (e) Commencement and Entry

Ref 2

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