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As per the PCT Guide,

the purpose of such informal comments is to give the applicant an opportunity to rebut the written opinion of the International Searching Authority in the event that international preliminary examination is not requested.

However it seems there will be no comment or rebuttal from any office of the PCT and these comments may be (or may be not) considered in the national phase for each examiner.

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3

My personal experience is that informal comments have never improved our position in any way. In the national/regional phases, the same objections have been raised by the same patent office acting as ISA, and by other patent offices.

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